产品货号：
Z24169
中文名称：
PIAS4抗体
英文名称：
Anti-PIAS4 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PIAS4 Antibody |
| 指标别名 | E3 SUMO protein ligase PIAS4;PIAS gamma;PIAS4;Piasg;PIASY;ZMIZ6 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC |
| 基因名称 | PIAS4 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | PIAS4 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human PIAS4.The immunogen is located within amino acids 50 - 100 of PIAS4. |
| 计算分子量 | 57kDa |
| 成分 | PIAS4 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | PIAS4 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | The PIAS (protein inhibitor of activated STAT) proteins play a crucial role as transcriptional coregulators in various cellular pathways,including the STAT,p53 and the steroid hormone signaling pathway.The PIAS protein family includes at least five evolutionarily conserved genes,including PIAS4.The major function of the PIAS proteins is the control of gene transcription and can also act as small ubiquitin-like-modifier (SUMO) E3 ligases.PIAS4 interacts with p53 and blocks its ability to induce Bax and p21 transcription.PIAS4 is also important in the control of the ubiquitin-dependent proteasomal degradation of the Ets-1 transcription factor.PIAS4 has been implicated in the DNA-damage response pathway and is thought to work in combination with PIAS1 for the productive association of 53BP1,BRCA1 and RNF168. |
| Uniprot ID | Q8N2W9 |
| 基因名全称 | Protein inhibitor of activated STAT,4 |
| 蛋白名全称 | Protein inhibitor of activated STAT,4 |
| 推荐稀释比 | PIAS4 antibody can be used for detection of PIAS4 by Western blot at 1μg/mL.Antibody can also be used for immunohistochemistry starting at 5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples and Immunohistochemistry in rat samples.All other applications and species not yet tested. |
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